"However successful a theory or law may have been in the past, directly it fails to interpret new discoveries its work is finished, and it must be discarded or modified. However plausible the hypothesis, it must be ever ready for sacrifice on the altar of observation." (Joseph W Mellor, "A Comprehensive Treatise on Inorganic and Theoretical Chemistry", 1922)
"Heuristic reasoning is reasoning not regarded as final and strict but as provisional and plausible only, whose purpose is to discover the solution of the present problem. We are often obliged to use heuristic reasoning. We shall attain complete certainty when we shall have obtained the complete solution, but before obtaining certainty we must often be satisfied with a more or less plausible guess. We may need the provisional before we attain the final. We need heuristic reasoning when we construct a strict proof as we need scaffolding when we erect a building." (George Pólya, "How to Solve It", 1945)
"The scientist who discovers a theory is usually guided to his discovery by guesses; he cannot name a method by means of which he found the theory and can only say that it appeared plausible to him, that he had the right hunch or that he saw intuitively which assumption would fit the facts." (Hans Reichenbach, "The Rise of Scientific Philosophy", 1951)
"In plausible reasoning the principal thing is to distinguish... a more reasonable guess from a less reasonable guess." (George Pólya, "Mathematics and plausible reasoning" Vol. 1, 1954)
"One feature [...] which requires much more justification than is usually given, is the setting up of unplausible null hypotheses. For example, a statistician may set out a test to see whether two drugs have exactly the same effect, or whether a regression line is exactly straight. These hypotheses can scarcely be taken literally." (Cedric A B Smith, "Book review of Norman T. J. Bailey: Statistical Methods in Biology", Applied Statistics 9, 1960)
"[…] the social scientist who lacks a mathematical mind and regards a mathematical formula as a magic recipe, rather than as the formulation of a supposition, does not hold forth much promise. A mathematical formula is never more than a precise statement. It must not be made into a Procrustean bed - and that is what one is driven to by the desire to quantify at any cost. It is utterly implausible that a mathematical formula should make the future known to us, and those who think it can, would once have believed in witchcraft. The chief merit of mathematicization is that it compels us to become conscious of what we are assuming." (Bertrand de Jouvenel, "The Art of Conjecture", 1967)
"In all scientific fields, theory is frequently more important than experimental data. Scientists are generally reluctant to accept the existence of a phenomenon when they do not know how to explain it. On the other hand, they will often accept a theory that is especially plausible before there exists any data to support it." (Richard Morris, 1983)
"The degree of confirmation assigned to any given hypothesis is sensitive to properties of the entire belief system [...] simplicity, plausibility, and conservatism are properties that theories have in virtue of their relation to the whole structure of scientific beliefs taken collectively. A measure of conservatism or simplicity would be a metric over global properties of belief systems." (Jerry Fodor, "Modularity of Mind", 1983)
"Nonetheless, the basic principles regarding correlations between variables are not that difficult to understand. We must look for patterns that reveal potential relationships and for evidence that variables are actually related. But when we do spot those relationships, we should not jump to conclusions about causality. Instead, we need to weigh the strength of the relationship and the plausibility of our theory, and we must always try to discount the possibility of spuriousness." (Joel Best, "More Damned Lies and Statistics: How numbers confuse public issues", 2004)
"Reality dishes out experiences using probability, not plausibility." (Eliezer S Yudkowsky, "A Technical Explanation of Technical Explanation", 2005)
"Don’t just do the calculations. Use common sense to see whether you are answering the correct question, the assumptions are reasonable, and the results are plausible. If a statistical argument doesn’t make sense, think about it carefully - you may discover that the argument is nonsense."
"Facts and values are entangled in science. It's not because scientists are biased, not because they are partial or influenced by other kinds of interests, but because of a commitment to reason, consistency, coherence, plausibility and replicability. These are value commitments." (Alva Noë)
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