"[…] it is not necessary that these hypotheses should be true, or even probably; but it is enough if they provide a calculus which fits the observations […]" (Andrew Osiander, "On the Revolutions of the Heavenly Spheres", 1543)
"The art of discovering the causes of phenomena, or true hypothesis, is like the art of decyphering, in which an ingenious conjecture greatly shortens the road." (Gottfried W Leibniz, "New Essays Concerning Human Understanding", 1704) [published 1765]
"In order to shake a hypothesis, it is sometimes not necessary to do anything more than push it as far as it will go." (Denis Diderot, "On the Interpretation of Nature", 1753)
"No hypothesis can lay claim to any value unless it assembles many phenomena under one concept." (Johann Wolfgang von Goethe, [letter to Sommering] 1795)
"Induction, analogy, hypotheses founded upon facts and rectified continually by new observations, a happy tact given by nature and strengthened by numerous comparisons of its indications with experience, such are the principal means for arriving at truth." (Pierre-Simon Laplace, "A Philosophical Essay on Probabilities", 1814)
"The hypothesis is like the captain, and the observations like the soldiers of an army: while he appears to command them, and in this way to work his own will, he does in fact derive all his power of conquest from their obedience, and becomes helpless and useless if they mutiny." (William Whewell, "Philosophy of the Inductive Sciences", 1840)
"The process of scientific discovery is cautious and rigorous, not by abstaining from hypothesis, but by rigorously comparing hypotheses with facts, and by resolutely rejecting all which the comparison does not confirm." (William Whewell, "The Philosophy of the Inductive Sciences Founded Upon Their History" Vol. 2, 1840)
"When the hypothesis, of itself and without adjustment for the purpose, gives us the rule and reason of a class of facts not contemplated in its construction, we have a criterion of its reality, which has never yet been produced in favour of falsehood." (William Whewell, "The Philosophy of the Inductive Sciences", 1840)
"An hypothesis being a mere supposition, there are no other limits to hypotheses than those of the human imagination; we may, if we please, imagine, by way of accounting for an effect, some cause of a kind utterly unknown, and acting according to a law altogether fictitious." (John S Mill, "A System of Logic, Ratiocinative and Inductive", 1843)
"It appears, then, to be a condition of a genuinely scientific hypothesis, that it be not destined always to remain an hypothesis, but be certain to be either proved or disproved by [...] comparison with observed facts." (John S Mill, "A System of Logic, Ratiocinative and Inductive", 1843)
"The hypothesis, by suggesting observations and experiments, puts us upon the road to that independent evidence if it be really attainable; and till it be attained, the hypothesis ought not to count for more than a suspicion." (John S Mill, "A System of Logic, Ratiocinative and Inductive", 1843)
"The rules of scientific investigation always require us, when we enter the domains of conjecture, to adopt that hypothesis by which the greatest number of known facts and phenomena may be reconciled." (Matthew F Maury, "The Physical Geography of the Sea", 1855)
"An anticipative idea or an hypothesis is, then, the necessary starting point for all experimental reasoning. Without it, we could not make any investigation at all nor learn anything; we could only pile up sterile observations. If we experiment without a preconceived idea, we should move at random […]" (Claude Bernard, "An Introduction to the Study of Experimental Medicine", 1865)
"In scientific investigations, it is permitted to invent any hypothesis and, if it explains various large and independent classes of facts, it rises to the ranks of a well-grounded theory." (Charles Darwin, "The Variations of Animals and Plants Under Domestication" Vol. 1, 1868)
"The great tragedy of Science - the slaying of a beautiful hypothesis by an ugly fact." (Thomas H Huxley, "Biogenesis and abiogenesis", [address] 1870)
"[…] wrong hypotheses, rightly worked from, have produced more useful results than unguided observation." (Augustus de Morgan, "A Budget of Paradoxes", 1872)
"An hypothesis is only a habit - a habit of looking through a glass of one peculiar colour, which imparts its hue to all around it." (Frederick Marryat, "The King's Own", 1873)
"A discoverer is a tester of scientific ideas; he must not only be able to imagine likely hypotheses, and to select suitable ones for investigation, but, as hypotheses may be true or untrue, he must also be competent to invent appropriate experiments for testing them, and to devise the requisite apparatus and arrangements." (George Gore, "The Art of Scientific Discovery", 1878)
"The scientific discovery appears first as the hypothesis of an analogy; and science tends to become independent of the hypothesis." (William K Clifford, "Lectures and Essays", 1879)
"Every hypothesis must derive indubitable results from mechanically well-defined assumptions by mathematically correct methods." (Ludwig Boltzmann, "Certain Questions of the Theory of Gasses", Nature Vol. 51 (1322), 1895)
"For the truly scientific man, the hypothesis is destined solely to enable him to get the facts of nature in some definite order, an order which shall make apparent their connection with the great order and harmony which is believed to be present in the universe." (James M Baldwin, "The Processes of Life Revealed by the Microscope: A Plea for Physiological Histology", Science N.S. Vol. 2 (34), 1895)
"If the working hypothesis fails in any essential particular he [the scientist] is ready to modify or discard it. For the truly inspired investigator, one undoubted fact weighs more in the balance than a thousand theories." (James M Baldwin, "The Processes of Life Revealed by the Microscope: A Plea for Physiological Histology", Science N.S. Vol. 2 (34), 1895)
"In scientific investigations, it is permitted to invent any hypothesis and, if it explains various large and independent classes of facts, it rises to the ranks of a well-grounded theory." (Charles Darwin, "The Variations of Animals and Plants Under Domestication" Vol. 1, 1896)
"Entia non sunt multiplicanda praeter necessitatem. That is to say; before you try a complicated hypothesis, you should make quite sure that no simplification of it will explain the facts equally well." (Charles S Peirce," Pragmatism and Pragmaticism", [lecture] 1903)
"A false hypothesis, if it serve as a guide for further enquiry, may, at the right stage of science, be as useful as, or more useful than, a truer one for which acceptable evidence is not yet at hand." (William C Dampier, "Science and the Human Mind, Science in the Ancient World", 1912)
"Without hypothesis there can be no progress in knowledge." (Max Verworn, "Irritability", 1913)
"The great difference between induction and hypothesis is that the former infers the existence of phenomena such as we have observed in cases which are similar, while hypothesis supposes something of a different kind from what we have directly observed, and frequently something which it would be impossible for us to observe directly." (Charles S Peirce, "Chance, Love and Logic: Philosophical Essays, Deduction, Induction, Hypothesis", 1914)
"Theory is the best guide for experiment - that were it not for theory and the problems and hypotheses that come out of it, we would not know the points we wanted to verify, and hence would experiment aimlessly" (Henry Hazlitt, "Thinking as a Science", 1916)
"A good hypothesis in science must have other properties than those of the phenomenon it is immediately invoked to explain, otherwise it is not prolific enough." (William James, "Selected Papers on Philosophy", 1918)
"An indispensable hypothesis, even though still far from being a guarantee of success, is however the pursuit of a specific aim, whose lighted beacon, even by initial failures, is not betrayed." (Max Planck, [Nobel lecture] 1918)
"A hypothesis or theory is clear, decisive, and positive, but it is believed by no one but the man who created it. Experimental findings, on the other hand, are messy, inexact things, which are believed by everyone except the man who did the work." (Harlow Shapley, "Review of Scientific Instruments" Vol. 6, 1922)
"However successful a theory or law may have been in the past, directly it fails to interpret new discoveries its work is finished, and it must be discarded or modified. However plausible the hypothesis, it must be ever ready for sacrifice on the altar of observation." (Joseph W Mellor, "A Comprehensive Treatise on Inorganic and Theoretical Chemistry", 1922)
"Hypothesis, however, is an inference based on knowledge which is insufficient to prove its high probability." (Frederick L Barry, "The Scientific Habit of Thought", 1927)
"Abstraction is the detection of a common quality in the characteristics of a number of diverse observations […] A hypothesis serves the same purpose, but in a different way. It relates apparently diverse experiences, not by directly detecting a common quality in the experiences themselves, but by inventing a fictitious substance or process or idea, in terms of which the experience can be expressed. A hypothesis, in brief, correlates observations by adding something to them, while abstraction achieves the same end by subtracting something." (Herbert Dingle, Science and Human Experience, 1931)
"Science does not aim, primarily, at high probabilities. It aims at a high informative content, well backed by experience. But a hypothesis may be very probable simply because it tells us nothing, or very little." (Karl Popper, "The Logic of Scientific Discovery", 1934)
"All the theories and hypotheses of empirical science share this provisional character of being established and accepted ‘until further notice’, whereas a mathematical theorem, once proved, is established once and for all; it holds with that particular certainty which no subsequent empirical discoveries, however unexpected and extraordinary, can ever affect to the slightest extent." (Carl G Hempel, "Geometry and Empirical Science", 1935)
"In relation to any experiment we may speak of this hypothesis as the null hypothesis, and it should be noted that the null hypothesis is never proved or established, but is possibly disproved, in the course of experimentation. Every experiment may be said to exist only in order to give the facts a chance of disproving the null hypothesis." (Ronald Fisher, "The Design of Experiments", 1935)
"The laws of science are the permanent contributions to knowledge - the individual pieces that are fitted together in an attempt to form a picture of the physical universe in action. As the pieces fall into place, we often catch glimpses of emerging patterns, called theories; they set us searching for the missing pieces that will fill in the gaps and complete the patterns. These theories, these provisional interpretations of the data in hand, are mere working hypotheses, and they are treated with scant respect until they can be tested by new pieces of the puzzle." (Edwin P Whipple, "Experiment and Experience", [Commencement Address, California Institute of Technology] 1938)
"When two hypotheses are possible, we provisionally choose that which our minds adjudge to the simpler on the supposition that this Is the more likely to lead in the direction of the truth." (James H Jeans, "Physics and Philosophy" 3rd Ed., 1943)
"We see what we want to see, and observation conforms to hypothesis." (Bergen Evans, "The Natural History of Nonsense", 1946)
"A successful hypothesis is not necessarily a permanent hypothesis, but it is one which stimulates additional research, opens up new fields, or explains and coordinates previously unrelated facts." (Farrington Daniels, "Outlines of Physical Chemistry", 1948)
"There would be cases where we would not want to accept an hypothesis even though the evidence gives a high d. c. [degree of confirmation] score, because we are fearful of the consequences of a wrong decision." (C West Churchman, "Theory of Experimental Inference", 1948)
"Hypothesis is a tool which can cause trouble if not used properly. We must be ready to abandon out hypothesis as soon as it is shown to be inconsistent with the facts." (William I B Beveridge, "The Art of Scientific Investigation", 1950)
"A collection of observable concepts in a purely formal hypothesis suggesting no analogy with anything would consequently not suggest either any directions for its own development." (Mary B Hesse, "Operational Definition and Analogy in Physical Theories", British Journal for the Philosophy of Science 2 (8), 1952)
"Whenever we attempt to test a hypothesis we naturally try to avoid errors in judging it. This seems to indicate the right way of proceeding: when choosing a test we should try to minimize the frequency of errors that may be committed in applying it." (Jerzy Neyman, "Lectures and Conferences on Mathematical Statistics", 1952)
"The only relevant test of the validity of a hypothesis is comparison of prediction with experience." (Milton Friedman, "Essays in Positive Economics", 1953)
"[…] the grand aim of all science […] is to cover the greatest possible number of empirical facts by logical deductions from the smallest possible number of hypotheses or axioms." (Albert Einstein, 1954)
"One must credit an hypothesis with all that has had to be discovered in order to demolish it." (Jean Rostand, "The substance of man", 1962)
"The formulation of a hypothesis carries with it an obligation to test it as rigorously as we can command skills to do so." (Peter Medawar, "Hypothesis and Imagination", 1963)
"Truth in science can be defined as the working hypothesis best suited to open the way to the next better one." (Konrad Lorenz, "On Aggression", 1963)
"The validation of a model is not that it is 'true' but that it generates good testable hypotheses relevant to important problems." (Richard Levins, "The Strategy of Model Building in Population Biology", 1966)
"All testing, all confirmation and disconfirmation of a hypothesis takes place already within a system. And this system is not a more or less arbitrary and doubtful point of departure for all our arguments; no it belongs to the essence of what we call an argument. The system is not so much the point of departure, as the element in which our arguments have their life." (Ludwig Wittgenstein, "On Certainty", 1969)
"Science consists simply of the formulation and testing of hypotheses based on observational evidence; experiments are important where applicable, but their function is merely to simplify observation by imposing controlled conditions." (Henry L Batten, "Evolution of the Earth", 1971)
"An experiment is a failure only when it also fails adequately to test the hypothesis in question, when the data it produces don't prove anything one way or the other." (Robert M Pirsig, "Zen and the Art of Motorcycle Maintenance", 1974)
"A hypothesis is empirical or scientific only if it can be tested by experience. […] A hypothesis or theory which cannot be, at least in principle, falsified by empirical observations and experiments does not belong to the realm of science." (Francisco J Ayala, "Biological Evolution: Natural Selection or Random Walk", American Scientist, 1974)
"A hypothesis will in the end become a truth when all phenomena let themselves be derived from it in a natural and in an obvious manner, when all these consequences are connected with one another and with the general reasons, in short, when that hypothesis is consistent in all its parts with itself." (Johann H Lambert, 1976)
"The essential function of a hypothesis consists in the guidance it affords to new observations and experiments, by which our conjecture is either confirmed or refuted." (Ernst Mach, "Knowledge and Error: Sketches on the Psychology of Enquiry", 1976)
"Be suspicious of a theory if more and more hypotheses are needed to support it as new facts become available, or as new considerations are brought to bear." (Sir Fred Hoyle & Nalin C Wickramasinghe, "Evolution from Space", 1981)
"All interpretations made by a scientist are hypotheses, and all hypotheses are tentative. They must forever be tested and they must be revised if found to be unsatisfactory. Hence, a change of mind in a scientist, and particularly in a great scientist, is not only not a sign of weakness but rather evidence for continuing attention to the respective problem and an ability to test the hypothesis again and again." (Ernst Mayr, "The Growth of Biological Thought: Diversity, Evolution and Inheritance", 1982)
"Don't just read it; fight it! Ask your own question, look for your own examples, dicover your own proofs. Is the hypothesis necessary? Is the converse true? What happens in the classical special case? What about the degenerate cases? Where does the proof use the hypothesis?" (Paul R Halmos, "I Want to be a Mathematician", 1985)
"Beware of the problem of testing too many hypotheses; the more you torture the data, the more likely they are to confess, but confessions obtained under duress may not be admissible in the court of scientific opinion." (Stephen M Stigler, "Testing Hypotheses or fitting Models? Another Look at Mass Extinctions" [in "Neutral Models in Biology"], 1987)
"All science is based on models, and every scientific model comprises three distinct stages: statement of well-defined hypotheses; deduction of all the consequences of these hypotheses, and nothing but these consequences; confrontation of these consequences with observed data." (Maurice Allais, "An Outline of My Main Contributions to Economic Science", [Noble lecture] 1988)
"Any physical theory is always provisional, in the sense that it is only a hypothesis: you can never prove it. No matter how many times the results of experiments agree with some theory, you can never be sure that the next time the result will not contradict the theory." (Stephen Hawking, "A Brief History of Time", 1988)
"The heart of the scientific method is the problem-hypothesis-test process. And, necessarily, the scientific method involves predictions. And predictions, to be useful in scientific methodology, must be subject to test empirically." (Paul Davies, "The Cosmic Blueprint: New Discoveries in Nature's Creative Ability to, Order the Universe", 1988)
"The model and the theory it represents must be accepted, at least temporarily, or rejected, depending on the agreement or disagreement between observed data and the hypotheses and implications of the model. When neither the hypotheses nor the implications of a theory can be confronted with the real world, that theory is devoid of any scientific interest. Mere logical, even mathematical, deduction remains worthless in terms of the understanding of reality if it is not closely linked to that reality." (Maurice Allais, "An Outline of My Main Contributions to Economic Science", [Noble lecture] 1988)
"A fact is a simple statement that everyone believes. It is innocent, unless found guilty. A hypothesis is a novel suggestion that no one wants to believe. It is guilty, until found effective." (Edward Teller, "Conversations on the Dark Secrets of Physics", 1991)
"Visualizations can be used to explore data, to confirm a hypothesis, or to manipulate a viewer. [...] In exploratory visualization the user does not necessarily know what he is looking for. This creates a dynamic scenario in which interaction is critical. [...] In a confirmatory visualization, the user has a hypothesis that needs to be tested. This scenario is more stable and predictable. System parameters are often predetermined." (Usama Fayyad et al, "Information Visualization in Data Mining and Knowledge Discovery", 2002)
"[…] a conceptual model is a diagram connecting variables and constructs based on theory and logic that displays the hypotheses to be tested." (Mary W Celsi et al, "Essentials of Business Research Methods", 2011)
"Data science is an iterative process. It starts with a hypothesis (or several hypotheses) about the system we’re studying, and then we analyze the information. The results allow us to reject our initial hypotheses and refine our understanding of the data. When working with thousands of fields and millions of rows, it’s important to develop intuitive ways to reject bad hypotheses quickly." (Phil Simon, "The Visual Organization: Data Visualization, Big Data, and the Quest for Better Decisions", 2014)
"Observation and experiment, without a rational hypothesis, is like a man groping at objects at random with his eyes shut." (Henry P Tappan, "Elements of Logic", 2015)
"A hypothesis is a starting point for an investigation. When you hypothesize, you make a claim about why something might be the case, based on limited data, to offer an explanation or a path forward. You wouldn’t make a proposition about something you are certain of. You may not have enough evidence yet to even convince you that it’s true. But making such a claim puts a stake in the ground that suggests a path for focused analysis." (Eben Hewitt, "Technology Strategy Patterns: Architecture as strategy" 2nd Ed., 2019)
"Data science is, in reality, something that has been around for a very long time. The desire to utilize data to test, understand, experiment, and prove out hypotheses has been around for ages. To put it simply: the use of data to figure things out has been around since a human tried to utilize the information about herds moving about and finding ways to satisfy hunger. The topic of data science came into popular culture more and more as the advent of ‘big data’ came to the forefront of the business world." (Jordan Morrow, "Be Data Literate: The data literacy skills everyone needs to succeed", 2021)
"Pure data science is the use of data to test, hypothesize, utilize statistics and more, to predict, model, build algorithms, and so forth. This is the technical part of the puzzle. We need this within each organization. By having it, we can utilize the power that these technical aspects bring to data and analytics. Then, with the power to communicate effectively, the analysis can flow throughout the needed parts of an organization." (Jordan Morrow, "Be Data Literate: The data literacy skills everyone needs to succeed", 2021)
